Seminario – DIFFERENT ASPECTS OF THROMBIN GENERATION

Venerdì, 22 luglio si svolgerà, presso l’aula conferenze del parco tecnologico, il seminario “DIFFERENT ASPECTS OF THROMBIN GENERATION” organizzato dal team di Epidemiologia e Prevenzione Neuromed. Gradito ospite sarà Bas de Laat, General Director, Synapse BV.

SEMINARI

DEL DIPARTIMENTO DI EPIDEMIOLOGIA E PREVENZIONE

VENERDì, 22 LUGLIO 2016 – Ore 12.00- Sala Conferenze ex Polo Didattico

DIFFERENT ASPECTS OF THROMBIN GENERATION

Ospite:  Bas de Laat – General Director, Synapse  BV

CARIM School for Cardiovascular Diseases

Maastricht University Medical Centre
Maastricht, The Netherlands
 Thrombin is a pivotal player in the coagulation system. In clotting blood a transient wave of thrombin appears after a lag time. Clotting occurs at the start of the wave. The amount of thrombin formed reflects the function of the hemostatic system much better than the clotting time does: “The more thrombin the less bleeding but the more thrombosis, the less thrombin the more bleeding but the less thrombosis” has been shown to hold for congenital and acquired tendencies to venous thrombosis and bleeding and under all variants of antithrombotic treatment. The situation with arterial thrombosis is less clear. Calibrated automated thrombinography (CAT) allows quantitative assessment of the thrombin generation (TG) curve in platelet poor as well as in platelet rich plasma. Procedures to measure TG in whole blood and at the point of care are under development. TG measurement in platelet-rich plasma underlines the close cooperation between platelets and the clotting system and challenges the traditional division between primary and secondary hemostasis
Il Seminario è aperto a tutto il personale Neuromed